Shire Raises Earnings Guidance After Record Sales Growth

LONDON—Shire PLC raised its earnings forecast after reporting record sales growth, demonstrating the lure of the Dublin-based drug maker after AbbVie Inc. pulled out of a $54 billion takeover.

AbbVie’s change of heart—for which it cited changes to the U.S. tax system—shocked the market and caused Shire’s shares to drop by almost a third. Yet despite the failed deal, Shire’s shares have risen 42% in London this year, including a 4%...